Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24126676 | 0.86 | ACHE (0.52) | ACHENR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL9461734 | 0.83 | DKK1 (0.50) | KDM4EALDH1A1HSD17B10HPGDCYP2C19 | |
| Hydrochloric Acid SCHEMBL27461247 | 0.82 | DKK1 (0.49) | KDM4EALDH1A1HSD17B10HPGDCYP2C19 | |
| SCHEMBL26684427 | 0.81 | ACACB (0.42) | ACHENR1H2NR1H3 | |
| SCHEMBL30338644 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10HPGDCYP2C19 | |
| SCHEMBL25294745 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10HPGDCYP2C19 | |
| Hydrochloric Acid SCHEMBL25263828 | 0.80 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10HPGDCYP2C19 | |
| SCHEMBL9462294 | 0.80 | DKK1 (0.53) | KDM4EALDH1A1HSD17B10HPGDCYP2C19 | |
| Hydrochloric Acid SCHEMBL30338561 | 0.80 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10HPGDCYP2C19 | |
| SCHEMBL25816539 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339937-A1 | CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS | SATO PHARMACEUTICAL CO., LTD. (JP) | 2023-10-26 | — | — | US | disclosed |
| US-20230339937-A1 | CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS | SATO PHARMACEUTICAL CO., LTD. (JP) | 2023-10-26 | — | — | US | disclosed |
| WO-2021256569-A1 | CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS | 佐藤製薬株式会社 | 2021-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339937-A1 | CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS | HPGDS, PTGS1, PTGIS | ACHE 3701/4885NR1H2 108/4885NR1H3 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.