SCHEMBL24133258

SCHEMBL24133258

CC(C)(C)c1cc2nc(I)oc2cc1C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
GFER P55789 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24910475 0.78 L3MBTL1 (0.43) LMNAESR1ESR2NPC1RAB9A
SCHEMBL20049355 0.74 CSNK1D (0.42) ESR1ESR2NPC1RAB9AGFER
SCHEMBL23095285 0.74 NPC1 (0.48) NPC1RAB9AGFER
SCHEMBL22337709 0.72 L3MBTL1 (0.44) LMNANPC1RAB9A
SCHEMBL24133257 0.71 AHR (0.41) LMNAESR1ESR2
SCHEMBL21168121 0.71 L3MBTL1 (0.43) LMNANPC1RAB9A
SCHEMBL24133261 0.69 NQO2 (0.42) NPC1
SCHEMBL20663406 0.68 NQO2 (0.43) LMNAESR1ESR2NPC1RAB9A
SCHEMBL24133264 0.67 RAB9A (0.58) LMNANPC1RAB9A
SCHEMBL24133266 0.67 KDM4E (0.59) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11209582-B2 Composition, curable composition, cured film, near infrared cut filter, infrared transmitting filter, solid image pickup element, infrared sensor, and camera module FUJIFILM CORPORATION (JP) 2021-12-28 US disclosed