SCHEMBL21168121

SCHEMBL21168121

Cc1nc2cc3nc(I)oc3cc2o1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
GAA P10253 2/20 0.43
CHRNB2 P17787 1/20 0.42
CHRNA4 P43681 1/20 0.42
POLB P06746 2/20 0.37
ALDH1A1 P00352 2/20 0.37
RAB9A P51151 5/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
NPC1 O15118 3/20 0.36
STAT1 P42224 1/20 0.36
KDM4E B2RXH2 3/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ELANE P08246 4/20 0.33
LMNA P02545 1/20 0.33
TAS1R3 Q7RTX0 3/20 0.33
TAS1R1 Q7RTX1 3/20 0.33
LRRK2 Q5S007 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22337709 0.94 L3MBTL1 (0.44) L3MBTL1GAACHRNB2CHRNA4POLB
SCHEMBL9912823 0.87 L3MBTL1 (0.52) L3MBTL1GAACHRNB2CHRNA4POLB
SCHEMBL2756560 0.80 L3MBTL1 (0.53) L3MBTL1GAACHRNB2CHRNA4POLB
SCHEMBL19914276 0.75 L3MBTL1 (0.46) L3MBTL1GAACHRNB2CHRNA4POLB
SCHEMBL862784 0.74 L3MBTL1 (0.48) L3MBTL1GAACHRNB2CHRNA4POLB
SCHEMBL31486630 0.74 L3MBTL1 (0.48) L3MBTL1GAACHRNB2CHRNA4POLB
SCHEMBL13986881 0.73 GAA (0.45) L3MBTL1GAACHRNB2CHRNA4POLB
SCHEMBL24302790 0.73 CHRNB2 (0.38) CHRNB2CHRNA4
SCHEMBL24133257 0.72 AHR (0.41) GAAALDH1A1MAPTLMNA
SCHEMBL24133264 0.72 RAB9A (0.58) L3MBTL1GAAPOLBALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225147-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-11637244-B2 Light-emitting material, compound, and organic light-emitting element KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-04-25 US disclosed
US-11335872-B2 Organic light-emitting device KYULUX, INC. (JP) 2022-05-17 US disclosed
US-11199776-B2 Resin composition TORAY INDUSTRIES, INC. (JP) 2021-12-14 US disclosed
US-20210234113-A1 ORGANIC LIGHT-EMITTING DEVICE KYULUX, INC. (JP) 2021-07-29 US disclosed
US-20200399246-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, AND ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2020-12-24 US disclosed
US-20200259112-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2020-08-13 US disclosed
US-20190348611-A1 LIGHT-EMITTING MATERIAL, COMPOUND, AND ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2019-11-14 US disclosed
US-20190221749-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, DELAYED FLUORESCENT MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190348611-A1 LIGHT-EMITTING MATERIAL, COMPOUND, AND ORGANIC LIGHT-EMITTING ELEMENT RPLP2, OPRD1, POLL L3MBTL1 410/4885GAA 3407/4885CHRNB2 2652/4885
US-11637244-B2 Light-emitting material, compound, and organic light-emitting element RPLP2, OPRD1, POLL L3MBTL1 410/4885GAA 3407/4885CHRNB2 2652/4885
US-11199776-B2 Resin composition SLC7A1, F12, SLCO2A1 L3MBTL1 3159/4885GAA 2034/4885CHRNB2 426/4885
US-20200399246-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, AND ORGANIC LIGHT-EMITTING ELEMENT SLC26A3, SLC43A1, SLC29A2 L3MBTL1 1542/4885GAA 3256/4885CHRNB2 1536/4885
US-20190221749-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, DELAYED FLUORESCENT MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT SLC43A1, SLC7A5, SLC39A3 L3MBTL1 1340/4885GAA 2835/4885CHRNB2 2946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.