SCHEMBL2413486

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13797489	0.81	TRPV4 (0.48)	HSD11B1MEN1KMT2ATSHRMAPK1
	SCHEMBL16186186	0.81	CA2 (0.41)	CA1CA2CA9TSHRMAPK1
	SCHEMBL16186187	0.79	CA1 (0.54)	CA1CA2KMT2AHCRTR1HCRTR2
	SCHEMBL29430629	0.79	HSD11B1 (0.48)	HSD11B1CA1CA2CA9CA7
	SCHEMBL1581780	0.79	HSD11B1 (0.48)	HSD11B1CA1CA2CA9CA7
	SCHEMBL12491217	0.78	CA2 (0.39)	CA1CA2CA9CA7CA14
	SCHEMBL13797487	0.78	AKR1B1 (0.44)	CA1CA2CA9TRPV4CA12
	SCHEMBL16507	0.76	TRPV4 (0.53)	HSD11B1CA1CA2CA9CA7
	SCHEMBL29209807	0.76	HSD11B1 (0.45)	HSD11B1CA1CA2CA9CA7
	SCHEMBL20590388	0.76	HSD11B1 (0.46)	HSD11B1CA1CA2CA9CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.