Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136162 | 0.83 | CYP11B1 (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL24136204 | 0.78 | L3MBTL1 (0.35) | — | |
| SCHEMBL22434776 | 0.77 | CYP11B1 (0.36) | CYP11B1CYP11B2CYP1A2CYP2A6 | |
| SCHEMBL22434866 | 0.68 | HSD11B1 (0.36) | CYP11B1CYP11B2 | |
| SCHEMBL24136193 | 0.65 | HRH4 (0.33) | CYP1A2 | |
| SCHEMBL20505289 | 0.62 | CHEK1 (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL24136183 | 0.61 | TRPM5 (0.35) | CYP1A2 | |
| SCHEMBL24136150 | 0.61 | AR (0.32) | CYP11B1CYP11B2 | |
| SCHEMBL24136189 | 0.61 | MEN1 (0.35) | — | |
| SCHEMBL29751862 | 0.59 | CES2 (0.40) | CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928836-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2021-12-29 | — | — | EP | disclosed |