Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22434653 | 0.79 | AR (0.40) | ARALDH1A1 | |
| SCHEMBL24136167 | 0.67 | IMPDH2 (0.37) | ARKDM4EALDH1A1 | |
| SCHEMBL20505119 | 0.67 | SMN1; SMN2 (0.41) | ARKDM4EALDH1A1HPGD | |
| SCHEMBL20604986 | 0.63 | AR (0.44) | AR | |
| SCHEMBL26581297 | 0.63 | TSHR (0.38) | ARKDM4EALDH1A1HSD17B10 | |
| SCHEMBL20504985 | 0.61 | DAO (0.49) | AR | |
| SCHEMBL18000433 | 0.59 | CMA1 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL24136218 | 0.59 | DYRK1A (0.36) | ARKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31257785 | 0.58 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL186269 | 0.58 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928836-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2021-12-29 | — | — | EP | disclosed |