Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | NQO2 | P16083 | 3/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136185 | 0.83 | CYP19A1 (0.38) | L3MBTL1CYP19A1NQO2NQO1KMT2A | |
| SCHEMBL22434669 | 0.79 | CYP19A1 (0.40) | L3MBTL1CYP19A1NQO2NQO1KMT2A | |
| SCHEMBL22434659 | 0.78 | L3MBTL1 (0.41) | L3MBTL1CYP19A1NQO2NQO1KMT2A | |
| SCHEMBL22434808 | 0.74 | IMPDH2 (0.38) | L3MBTL1CYP19A1NQO2NQO1LMNA | |
| SCHEMBL8015186 | 0.71 | RHEB (0.47) | L3MBTL1CYP19A1NQO2KMT2AHTT | |
| SCHEMBL20505016 | 0.70 | HASPIN (0.39) | CYP19A1NQO2LMNAKDM4EALDH1A1 | |
| SCHEMBL29763984 | 0.70 | HASPIN (0.39) | CYP19A1NQO2LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL23152610 | 0.69 | HASPIN (0.38) | KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL24136189 | 0.68 | MEN1 (0.35) | CYP19A1NQO2NQO1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL23152635 | 0.67 | POLB (0.37) | L3MBTL1KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928836-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2021-12-29 | — | — | EP | disclosed |