Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2276436 | 0.81 | MTNR1B (0.44) | RHEBMTNR1BMTNR1AHTR2C | |
| SCHEMBL23282978 | 0.80 | MTNR1B (0.46) | MTNR1BMTNR1AHTR2CKDM4EALDH1A1 | |
| SCHEMBL434299 | 0.77 | CYP19A1 (0.46) | HTR2CCYP19A1NQO2KDM4EALDH1A1 | |
| SCHEMBL26473 | 0.76 | MTNR1B (0.67) | MTNR1BMTNR1ACYP19A1MAPTKMT2A | |
| SCHEMBL8025948 | 0.76 | DRD2 (0.42) | RHEBMTNR1B | |
| SCHEMBL8015473 | 0.76 | MAPT (0.42) | RHEBDHFRHTR2CKDM4EALDH1A1 | |
| SCHEMBL17680608 | 0.76 | RHEB (0.43) | RHEBDHFRKDM4EALDH1A1MEN1 | |
| SCHEMBL25171221 | 0.76 | DHFR (0.42) | RHEBDHFRNQO2KDM4EALDH1A1 | |
| SCHEMBL19644367 | 0.74 | NR4A2 (0.46) | KDM4EALDH1A1MEN1MAPTHPGD | |
| SCHEMBL24451609 | 0.73 | HTR2C (0.43) | MTNR1BMTNR1AHTR2CCYP19A1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11384090-B2 | Spiropyrrolidine derived antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2022-07-12 | — | — | US | disclosed |
| US-20220162216-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2022-05-26 | — | — | US | disclosed |
| WO-2000061554-A1 | 1-AMINO ETHYLINDOLE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2000-10-19 | — | — | WO | disclosed |
| WO-2000061553-A1 | 2-AMINOETHYL-INDOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2000-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11384090-B2 | Spiropyrrolidine derived antiviral agents | ACE, ACE2, REN | RHEB 836/4885MTNR1B 3417/4885MTNR1A 3792/4885 |
| US-20220162216-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ACE, ACE2, REN | RHEB 536/4885MTNR1B 3569/4885MTNR1A 3825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.