Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | RXRB | P28702 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5067089 | 0.86 | LMNA (0.70) | L3MBTL1LMNAMAPK1KDM4EHPGD | |
| SCHEMBL30885868 | 0.86 | LMNA (0.70) | L3MBTL1LMNAMAPK1KDM4EHPGD | |
| SCHEMBL19043148 | 0.85 | L3MBTL1 (0.72) | L3MBTL1LMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL2741520 | 0.85 | LMNA (0.54) | L3MBTL1LMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL10082820 | 0.84 | ALDH1A1 (0.57) | L3MBTL1LMNAALDH1A1KMT2ATSHR | |
| SCHEMBL2777259 | 0.83 | L3MBTL1 (0.64) | L3MBTL1LMNAMAPK1KDM4EHPGD | |
| SCHEMBL31302989 | 0.83 | L3MBTL1 (0.64) | L3MBTL1LMNAMAPK1KDM4EHPGD | |
| SCHEMBL22434873 | 0.83 | L3MBTL1 (0.59) | L3MBTL1LMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL15063356 | 0.82 | LMNA (0.74) | L3MBTL1LMNAMAPK1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL2777750 | 0.81 | L3MBTL1 (0.62) | L3MBTL1LMNAMAPK1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928836-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2021-12-29 | — | — | EP | disclosed |