Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 14/20 | 0.55 |
| ▸ | SLC22A12 | Q96S37 | 14/20 | 0.55 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24137494 | 0.83 | CYP11B2 (0.46) | XDHSLC22A12IKBKBMKNK2 | |
| SCHEMBL24137914 | 0.81 | LTA4H (0.44) | XDHSLC22A12IKBKBMKNK2 | |
| SCHEMBL24137798 | 0.78 | XDH (0.50) | XDHSLC22A12PDPK1PIK3CG | |
| SCHEMBL24137728 | 0.77 | KLK5 (0.43) | — | |
| SCHEMBL24137851 | 0.77 | KDM4E (0.41) | MKNK2 | |
| SCHEMBL4192415 | 0.74 | XDH (0.59) | XDHSLC22A12MKNK1MKNK2DHODH | |
| SCHEMBL2841435 | 0.74 | MEN1 (0.56) | XDHSLC22A12PDPK1MKNK1MKNK2 | |
| SCHEMBL24137794 | 0.73 | CYP11B2 (0.46) | XDHSLC22A12MKNK2 | |
| SCHEMBL4187260 | 0.73 | XDH (0.63) | XDHSLC22A12DHODH | |
| SCHEMBL30065768 | 0.72 | XDH (0.48) | XDHSLC22A12PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263129-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-30 | — | — | WO | disclosed |