Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28063108 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HSD17B10MAPTL3MBTL1ALOX12 | |
| SCHEMBL11757533 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HSD17B10L3MBTL1CYP3A4ALOX15 | |
| SCHEMBL19268415 | 0.80 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPTL3MBTL1ALOX12 | |
| SCHEMBL4192415 | 0.79 | XDH (0.59) | XDHSLC22A12ALDH1A1HSD17B10MAPT | |
| Diphenylamine SCHEMBL21753932 | 0.79 | ALDH1A1 (0.74) | ALDH1A1HSD17B10MAPTL3MBTL1ALOX12 | |
| SCHEMBL2841435 | 0.76 | MEN1 (0.56) | XDHSLC22A12ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL21915556 | 0.75 | FDPS (0.56) | XDHSLC22A12PIK3CBCNR1 | |
| SCHEMBL24137798 | 0.73 | XDH (0.50) | XDHSLC22A12MAPTCYP1A2CYP3A4 | |
| SCHEMBL30065759 | 0.73 | XDH (0.41) | XDHSLC22A12ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL4187260 | 0.72 | XDH (0.63) | XDHSLC22A12CYP3A4TSHRCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12351556-B2 | Pyridin-2(1H)one derivatives, their preparation and their use for the treatment of pain | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2025-07-08 | — | — | US | disclosed |
| US-20220363643-A1 | NOVEL PYRIDIN-2(1H)ONE DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR THE TREATMENT OF PAIN | CENTRE HOSPITALIER UNIVERSITAIRE DE CLERMONT-FD (FR) | 2022-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220363643-A1 | NOVEL PYRIDIN-2(1H)ONE DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR THE TREATMENT OF PAIN | P2RX3, OPRL1, P2RX6 | XDH 1051/4885SLC22A12 3909/4885ALDH1A1 836/4885 |
| US-12351556-B2 | Pyridin-2(1H)one derivatives, their preparation and their use for the treatment of pain | P2RX3, P2RX6, P2RX4 | XDH 938/4885SLC22A12 3755/4885ALDH1A1 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.