Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24137734 | 0.87 | CYP1A2 (0.40) | FYNMAP4K4MEN1ALDH1A1KMT2A | |
| SCHEMBL24137834 | 0.84 | KCNH2 (0.44) | FYNMAP4K4ALDH1A1HSD17B10AKT1 | |
| SCHEMBL24137728 | 0.82 | KLK5 (0.43) | SCN2ASCN10AFYNRAB9ANPC1 | |
| SCHEMBL24137796 | 0.77 | LTA4H (0.42) | FYNAKT1HDAC3HDAC1 | |
| SCHEMBL24137798 | 0.77 | XDH (0.50) | FYNGFERMEN1KMT2AMAPT | |
| SCHEMBL24137537 | 0.76 | DHFR (0.41) | SCN2ASCN10AFYNRAB9ANPC1 | |
| SCHEMBL24137727 | 0.75 | JAK2 (0.52) | MAPK8MAP4K4AKT1 | |
| SCHEMBL24137909 | 0.72 | CCNC (0.54) | RAB9ANPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL22191473 | 0.72 | GAA (0.53) | SCN2ASCN10AMEN1KMT2AAKT1 | |
| SCHEMBL24137469 | 0.70 | CYP11B2 (0.47) | FYNAKT1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263129-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-30 | — | — | WO | disclosed |