⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19597450 | 0.69 | — | — | |
| SCHEMBL789073 | 0.67 | HTR7 (0.50) | — | |
| SCHEMBL366049 | 0.67 | HTR7 (0.50) | — | |
| SCHEMBL10537391 | 0.67 | HTR1A (0.34) | — | |
| SCHEMBL11938142 | 0.65 | HTR7 (0.48) | — | |
| SCHEMBL1451190 | 0.65 | — | — | |
| SCHEMBL11938139 | 0.65 | HTR7 (0.48) | — | |
| Hydrochloric Acid SCHEMBL3379346 | 0.65 | HTR7 (0.48) | — | |
| SCHEMBL7004901 | 0.65 | — | — | |
| SCHEMBL19175807 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872147-B1 | METHOD FOR MAKING CHIRAL OLIGONUCLEOTIDES | WAVE LIFE SCIENCES LTD (SG) | 2022-12-21 | — | — | EP | disclosed |
| WO-2021263250-A2 | METHOD OF TREATING SEVERE FORMS OF PULMONARY HYPERTENSION | REVERSPAH LLC (US) | 2021-12-30 | — | — | WO | disclosed |