Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 known ✓ | P34969 | 4/20 | 0.48 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 known ✓ | P14416 | 1/20 | 0.48 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.48 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.39 |
| ▸ | HRH2 known ✓ | P25021 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366049 | 0.96 | HTR7 (0.50) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL7202651 | 0.84 | — | — | |
| SCHEMBL8814666 | 0.83 | HTR7 (0.46) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL6420602 | 0.83 | HTR7 (0.46) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL18215308 | 0.82 | HTR1A (0.40) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL18210498 | 0.82 | TSHR (0.56) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL15337873 | 0.80 | — | — | |
| SCHEMBL17540480 | 0.80 | HTR1A (0.39) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL17919285 | 0.78 | PRMT3 (0.55) | HTR7HTR1ADRD2HTR2APRMT3 | |
| SCHEMBL22307428 | 0.78 | HTR1A (0.37) | HTR7HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12292363-B2 | Method for preparing biological material having excellent light-transmitting property | RIKEN (JP) | 2025-05-06 | — | — | US | claimed |
| US-20220381657-A1 | METHOD FOR PREPARING BIOLOGICAL MATERIAL HAVING EXCELLENT LIGHT-TRANSMITTING PROPERTY | RIKEN (JP) | 2022-12-01 | — | — | US | claimed |
| CN-114425238-B | Stain-resistant chlorine-resistant dual-functional polyamide composite reverse osmosis membrane and preparation method thereof | 自然资源部天津海水淡化与综合利用研究所 | 2022-11-25 | — | — | CN | claimed |
| CN-114425238-A | Stain-resistant chlorine-resistant dual-functional polyamide composite reverse osmosis membrane and preparation method thereof | 自然资源部天津海水淡化与综合利用研究所 | 2022-05-03 | — | — | CN | claimed |
| CN-110772648-B | Preparation method of RGD modified dendrimer coated CuS nanoparticles | 东华大学 | 2021-06-11 | — | — | CN | claimed |
| CN-110772648-A | Preparation method of RGD modified dendrimer coated CuS nanoparticles | 东华大学 | 2020-02-11 | — | — | CN | claimed |
| JP-8183743-A | — | — | None | — | — | JP | disclosed |
| US-12338244-B2 | Temozolomide compounds, polymers prepared therefrom, and method of treating a disease | UNIVERSITY OF MASSACHUSETTS (US) | 2025-06-24 | — | — | US | disclosed |
| US-20240254127-A1 | TEMOZOLOMIDE COMPOUNDS, POLYMERS PREPARED THEREFROM, AND METHOD OF TREATING A DISEASE | UNIVERSITY OF MASSACHUSETTS | 2024-08-01 | — | — | US | disclosed |
| US-11912709-B2 | Temozolomide compounds, polymers prepared therefrom, and method of treating a disease | UNIVERSITY OF MASSACHUSETTS (US) | 2024-02-27 | — | — | US | disclosed |
| US-20230052528-A1 | TASPASE1 INHIBITORS AND USES THEREOF | UNIV CALIFORNIA (US) | 2023-02-16 | — | — | US | disclosed |
| US-20220381657-A1 | METHOD FOR PREPARING BIOLOGICAL MATERIAL HAVING EXCELLENT LIGHT-TRANSMITTING PROPERTY | RIKEN (JP) | 2022-12-01 | — | — | US | disclosed |
| CN-114425238-B | Stain-resistant chlorine-resistant dual-functional polyamide composite reverse osmosis membrane and preparation method thereof | 自然资源部天津海水淡化与综合利用研究所 | 2022-11-25 | — | — | CN | disclosed |
| US-7550016-B2 | Sulfide dyes | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-06-23 | — | — | US | disclosed |
| US-20090100610-A1 | Mixture of Sulfide Dyes | CIBA CORPORATION | 2009-04-23 | — | — | US | disclosed |
| US-20090049620-A1 | Sulfide dyes | CIBA SPECIALTY CHEMICAL CORP. | 2009-02-26 | — | — | US | disclosed |
| CN-101326246-A | Mixture of sulfide dyes | CIBA SC HOLDING AG (CH) | 2008-12-17 | — | — | CN | disclosed |
| EP-1893694-A2 | SULFIDE DYES | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006136516-A2 | SULFIDE DYES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-12-28 | — | — | WO | disclosed |
| JP-H08183743-A | PRODUCTION OF DISULFIDE COMPOUND | SUMITOMO SEIKA CHEM CO LTD | 1996-07-16 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912709-B2 | Temozolomide compounds, polymers prepared therefrom, and method of treating a disease | PBRM1, MGMT, TOP1 | HTR7 3545/4885HTR1A 1074/4885DRD2 4518/4885 |
| US-20090100610-A1 | Mixture of Sulfide Dyes | KRT18, TST, ARSA | HTR7 1206/4885HTR1A 3227/4885DRD2 3615/4885 |
| US-20240254127-A1 | TEMOZOLOMIDE COMPOUNDS, POLYMERS PREPARED THEREFROM, AND METHOD OF TREATING A DISEASE | PBRM1, MGMT, TOP1 | HTR7 3545/4885HTR1A 1074/4885DRD2 4518/4885 |
| US-12338244-B2 | Temozolomide compounds, polymers prepared therefrom, and method of treating a disease | PBRM1, MGMT, TOP1 | HTR7 3545/4885HTR1A 1074/4885DRD2 4518/4885 |
| US-20230052528-A1 | TASPASE1 INHIBITORS AND USES THEREOF | RNASE1, TASP1, TPP1 | HTR7 4353/4885HTR1A 4244/4885DRD2 4860/4885 |
| US-20090049620-A1 | Sulfide dyes | KRT18, C9, CBR3 | HTR7 2120/4885HTR1A 2085/4885DRD2 3243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.