Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | CASP3 | P42574 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24153270 | 0.91 | TRPA1 (0.39) | MAOACASP3MAOBTRPA1MEN1 | |
| SCHEMBL24151570 | 0.89 | MAOA (0.41) | MAOACASP3MAOBTRPA1MEN1 | |
| SCHEMBL24152352 | 0.89 | MAOA (0.41) | MAOACASP3MAOBTRPA1RXFP1 | |
| SCHEMBL24151572 | 0.89 | CASP3 (0.41) | MAOACASP3MAOBTRPA1RXFP1 | |
| SCHEMBL24151566 | 0.89 | MAOA (0.56) | MAOACASP3MAOBTRPA1RXFP1 | |
| SCHEMBL24151567 | 0.88 | TRPA1 (0.55) | MAOACASP3MAOBTRPA1MAPT | |
| SCHEMBL24152355 | 0.88 | MAOA (0.41) | MAOACASP3MAOBTRPA1ALDH1A1 | |
| SCHEMBL24152818 | 0.83 | TRPA1 (0.34) | MAOACASP3MAOBTRPA1MEN1 | |
| SCHEMBL24153267 | 0.80 | TRPA1 (0.48) | MAOACASP3TRPA1CA12CA1 | |
| SCHEMBL24152458 | 0.80 | TRPA1 (0.35) | MAOACASP3MAOBTRPA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |