Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 14/20 | 0.41 |
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 8/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24153265 | 0.91 | TRPA1 (0.37) | CASP3MAOAMAOBTRPA1CASP7 | |
| SCHEMBL24152355 | 0.90 | MAOA (0.41) | CASP3MAOAMAOBTRPA1ALK | |
| SCHEMBL24152352 | 0.90 | MAOA (0.41) | CASP3MAOAMAOBTRPA1ALK | |
| SCHEMBL24151570 | 0.89 | MAOA (0.41) | CASP3MAOAMAOBTRPA1ALK | |
| SCHEMBL24151571 | 0.89 | MAOA (0.41) | CASP3MAOAMAOBTRPA1CASP7 | |
| SCHEMBL24151566 | 0.88 | MAOA (0.56) | CASP3MAOAMAOBTRPA1CASP7 | |
| SCHEMBL24151567 | 0.87 | TRPA1 (0.55) | CASP3MAOAMAOBTRPA1CASP7 | |
| SCHEMBL24152819 | 0.84 | RXFP1 (0.34) | CASP3MAOAMAOBTRPA1ALK | |
| SCHEMBL24153256 | 0.82 | TRPA1 (0.37) | CASP3MAOAMAOBTRPA1CASP7 | |
| SCHEMBL24152458 | 0.81 | TRPA1 (0.35) | CASP3MAOAMAOBTRPA1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |