Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | CASP3 | P42574 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152825 | 0.94 | TAS2R14 (0.35) | TRPA1S1PR4TAS2R14ALDH1A1KDM4E | |
| SCHEMBL24152355 | 0.91 | MAOA (0.41) | TRPA1S1PR4TAS2R14ALDH1A1SMN1; SMN2 | |
| SCHEMBL24153265 | 0.88 | TRPA1 (0.37) | TRPA1TAS2R14KDM4ELMNAMAOA | |
| SCHEMBL24152819 | 0.84 | RXFP1 (0.34) | TRPA1TAS2R14ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL24153267 | 0.82 | TRPA1 (0.48) | TRPA1TAS2R14MAOACASP3CASP7 | |
| SCHEMBL24153270 | 0.82 | TRPA1 (0.39) | TRPA1TAS2R14ALDH1A1KDM4ELMNA | |
| SCHEMBL24152818 | 0.82 | TRPA1 (0.34) | TRPA1TAS2R14KDM4ELMNAMAOA | |
| SCHEMBL24152504 | 0.82 | TAS2R14 (0.41) | TRPA1TAS2R14ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL24152493 | 0.82 | PTGS1 (0.37) | TRPA1TAS2R14KDM4ELMNAMAOA | |
| SCHEMBL24151572 | 0.82 | CASP3 (0.41) | TRPA1MAOACASP3MAOBALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |