Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 4/20 | 0.37 |
| ▸ | CASP7 | P55210 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152357 | 0.87 | TRPA1 (0.54) | TRPA1CASP3CASP7CA12CA1 | |
| SCHEMBL24152359 | 0.86 | TRPA1 (0.50) | TRPA1CASP3CASP7PTGS1PTGS2 | |
| SCHEMBL24151575 | 0.84 | TRPA1 (0.61) | TRPA1CASP3CASP7CA12CA1 | |
| SCHEMBL24151764 | 0.84 | TRPA1 (0.49) | TRPA1CASP3CASP7CA12CA1 | |
| SCHEMBL24152517 | 0.81 | TRPA1 (0.48) | TRPA1MAPTL3MBTL1POLBTDP1 | |
| SCHEMBL24152372 | 0.80 | TRPA1 (0.47) | TRPA1CASP3CASP7CA12CA2 | |
| SCHEMBL24151589 | 0.80 | TRPA1 (0.47) | TRPA1CASP3CASP7CA12CA1 | |
| SCHEMBL24152830 | 0.80 | TRPA1 (0.38) | TRPA1CASP3CASP7MAPTPOLB | |
| SCHEMBL24153249 | 0.80 | TRPA1 (0.41) | TRPA1CASP3PTGS1PTGS2CA12 | |
| SCHEMBL24152847 | 0.79 | TRPA1 (0.41) | TRPA1CASP3CASP7PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |