Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 4/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPA3 | P15088 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413866 | 0.84 | PPARA (0.46) | KMT2ASMN1; SMN2HTTMMP3MMP9 | |
| SCHEMBL2413872 | 0.84 | PPARA (0.46) | KMT2ASMN1; SMN2HTTMMP3MMP9 | |
| SCHEMBL2413869 | 0.84 | SLC15A1 (0.44) | KMT2ASMN1; SMN2HTTFOLH1MMP3 | |
| SCHEMBL1405655 | 0.82 | KMT2A (0.53) | KMT2ASMN1; SMN2MMP3MMP9CPA1 | |
| SCHEMBL9555874 | 0.82 | KMT2A (0.53) | KMT2ASMN1; SMN2MMP3MMP9CPA1 | |
| SCHEMBL11116485 | 0.81 | SMN1; SMN2 (0.48) | KMT2ASMN1; SMN2HTTFOLH1ALDH1A1 | |
| SCHEMBL18220621 | 0.80 | SLC1A1 (0.44) | KMT2ASMN1; SMN2HTTMMP3MMP9 | |
| SCHEMBL735424 | 0.79 | LTA4H (0.55) | SMN1; SMN2HTTFOLH1ALDH1A1LMNA | |
| SCHEMBL9574068 | 0.79 | MMP2 (0.57) | MMP3MMP2 | |
| SCHEMBL12162457 | 0.79 | MMP2 (0.57) | MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542554-A1 | PROCESSES FOR THE PREPARATION OF S1P1 RECEPTOR MODULATORS AND CRYSTALLINE FORMS THEREOF | Arena Pharmaceuticals, Inc. (US) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011109471-A1 | PROCESSES FOR THE PREPARATION OF S1P1 RECEPTOR MODULATORS AND CRYSTALLINE FORMS THEREOF | ARENA PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |