Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 12/20 | 0.45 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152391 | 0.84 | FLT3 (0.41) | NTRK1NTRK3MEN1KMT2AFLT3 | |
| SCHEMBL24152351 | 0.81 | NTRK1 (0.45) | NTRK1NTRK3MEN1KMT2AFLT3 | |
| SCHEMBL24152394 | 0.80 | TLK2 (0.46) | NTRK1FLT3RPS6KA3KDRPDGFRB | |
| SCHEMBL24152392 | 0.73 | MOGAT2 (0.45) | MEN1KMT2AFLT3RPS6KA3 | |
| SCHEMBL24152878 | 0.73 | MEN1 (0.39) | MEN1KMT2ATLK2 | |
| SCHEMBL7812244 | 0.71 | LRRK2 (0.56) | RPS6KA3PDGFRB | |
| SCHEMBL7812245 | 0.71 | LRRK2 (0.56) | RPS6KA3PDGFRB | |
| SCHEMBL24152858 | 0.70 | NTRK1 (0.46) | NTRK1MEN1KMT2ARPS6KA3TLK2 | |
| SCHEMBL24152544 | 0.69 | TLK2 (0.44) | MEN1KMT2AKDRPDGFRBTLK2 | |
| SCHEMBL6000844 | 0.68 | GSK3B (0.59) | NTRK1NTRK3KMT2AFLT3RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |