Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 5/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MGAT2 | Q10469 | 5/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.37 |
| ▸ | MGAT3 | Q09327 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152858 | 0.87 | NTRK1 (0.46) | NTRK1SRCSYKMEN1KMT2A | |
| SCHEMBL24152392 | 0.85 | MOGAT2 (0.45) | MEN1KMT2AFLT3MGAT2RPS6KA3 | |
| SCHEMBL24152421 | 0.84 | LMNA (0.44) | SRCSYK | |
| SCHEMBL24152849 | 0.84 | MGAT2 (0.49) | NTRK1SRCSYKMGAT2CDK2 | |
| SCHEMBL24152386 | 0.83 | PKM (0.39) | MGAT2 | |
| SCHEMBL24152477 | 0.82 | SYK (0.49) | SRCSYKMEN1KMT2AMGAT2 | |
| SCHEMBL24151523 | 0.82 | SYK (0.42) | NTRK1NTRK3SYKMEN1KMT2A | |
| SCHEMBL24152577 | 0.82 | SCN3A (0.53) | NTRK1SRCSYKMGAT2MOGAT2 | |
| SCHEMBL24152390 | 0.81 | NTRK1 (0.45) | NTRK1NTRK3MEN1KMT2AFLT3 | |
| SCHEMBL24151508 | 0.81 | IDO1 (0.47) | SYKKMT2AMGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |