Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 11/20 | 0.39 |
| ▸ | PAK4 | O96013 | 6/20 | 0.39 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152474 | 0.81 | CDK2 (0.45) | MEN1KMT2AGRK5PAK4 | |
| SCHEMBL24151583 | 0.75 | CDK2 (0.42) | MEN1KMT2APAK4TLK2 | |
| SCHEMBL24152391 | 0.75 | FLT3 (0.41) | MEN1KMT2ATLK2 | |
| SCHEMBL24152394 | 0.74 | TLK2 (0.46) | TLK2 | |
| SCHEMBL6000844 | 0.74 | GSK3B (0.59) | KMT2ATLK2 | |
| SCHEMBL6000847 | 0.74 | GSK3B (0.59) | KMT2ATLK2 | |
| SCHEMBL24152390 | 0.73 | NTRK1 (0.45) | MEN1KMT2ATLK2 | |
| SCHEMBL7812244 | 0.72 | LRRK2 (0.56) | — | |
| SCHEMBL7812245 | 0.72 | LRRK2 (0.56) | — | |
| SCHEMBL24152544 | 0.70 | TLK2 (0.44) | MEN1KMT2ATLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |