Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 6/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151798 | 0.90 | SYK (0.44) | SRCSYKNAMPTCYP19A1MGAT2 | |
| SCHEMBL24152849 | 0.90 | MGAT2 (0.49) | NTRK1SRCSYKMGAT2 | |
| SCHEMBL24151507 | 0.87 | SYK (0.53) | NTRK1SYKNAMPTCYP19A1TLK2 | |
| SCHEMBL24151508 | 0.87 | IDO1 (0.47) | SYKMGAT2KMT2A | |
| SCHEMBL24152351 | 0.87 | NTRK1 (0.45) | NTRK1SRCSYKMGAT2RPS6KA3 | |
| SCHEMBL24152477 | 0.85 | SYK (0.49) | SRCSYKMGAT2AKT1MEN1 | |
| SCHEMBL24152577 | 0.84 | SCN3A (0.53) | NTRK1SRCSYKNAMPTCYP19A1 | |
| SCHEMBL24152348 | 0.83 | SYK (0.47) | SRCSYKMGAT2 | |
| SCHEMBL24151529 | 0.83 | SYK (0.61) | NTRK1SRCSYKAKT1TLK2 | |
| SCHEMBL24152421 | 0.82 | LMNA (0.44) | SRCSYKNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |