Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | PAK4 | O96013 | 3/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152474 | 0.91 | CDK2 (0.45) | CDK2KDRPAK4PDPK1ALDH1A1 | |
| SCHEMBL24151592 | 0.84 | CDK2 (0.43) | CDK2KDRPDPK1NTRK1SYK | |
| SCHEMBL24152849 | 0.83 | MGAT2 (0.49) | CDK2PDPK1ALDH1A1CTDSP1NTRK1 | |
| SCHEMBL24151756 | 0.80 | TRPA1 (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL24152421 | 0.78 | LMNA (0.44) | ALDH1A1SYKSRC | |
| SCHEMBL24151550 | 0.78 | GAA (0.52) | PDPK1MEN1KMT2APRKDCTLK2 | |
| SCHEMBL24152348 | 0.78 | SYK (0.47) | CDK2KDRSYKSRCFCER2 | |
| SCHEMBL24151582 | 0.77 | PDPK1 (0.43) | CDK2PDPK1ALDH1A1CTDSP1SRC | |
| SCHEMBL24151597 | 0.77 | MGAT2 (0.49) | CDK2KDRALDH1A1SRCTLK2 | |
| SCHEMBL24152392 | 0.77 | MOGAT2 (0.45) | CDK2PDPK1ALDH1A1CTDSP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |