Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SCN1B | Q07699 | 3/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151583 | 0.91 | CDK2 (0.42) | CDK2KDRMEN1KMT2AALDH1A1 | |
| SCHEMBL24151592 | 0.84 | CDK2 (0.43) | CDK2KDRPDPK1SRCPRKDC | |
| SCHEMBL24152849 | 0.81 | MGAT2 (0.49) | CDK2ALDH1A1PDPK1SRCPRKDC | |
| SCHEMBL24152878 | 0.81 | MEN1 (0.39) | MEN1KMT2AGRK5PAK4 | |
| SCHEMBL24152348 | 0.80 | SYK (0.47) | CDK2KDRSRC | |
| SCHEMBL24151798 | 0.77 | SYK (0.44) | CDK2MEN1KMT2AALDH1A1PDPK1 | |
| SCHEMBL24151550 | 0.76 | GAA (0.52) | MEN1KMT2APDPK1PRKDC | |
| SCHEMBL24152477 | 0.76 | SYK (0.49) | CDK2MEN1KMT2AALDH1A1SRC | |
| SCHEMBL24151582 | 0.76 | PDPK1 (0.43) | CDK2ALDH1A1PDPK1SRCPRKDC | |
| SCHEMBL24151597 | 0.76 | MGAT2 (0.49) | CDK2KDRALDH1A1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |