Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 4/20 | 0.47 |
| ▸ | PORCN | Q9H237 | 3/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 5/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29968208 | 1.00 | DYRK1A (0.48) | DYRK1AHAO1PORCNCCNCCDK8 | |
| SCHEMBL31166180 | 1.00 | DYRK1A (0.48) | DYRK1AHAO1PORCNCCNCCDK8 | |
| SCHEMBL23319895 | 1.00 | DYRK1A (0.48) | DYRK1AHAO1PORCNCCNCCDK8 | |
| SCHEMBL25463836 | 0.86 | PRKAG1 (0.37) | HAO1PORCNPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL23319946 | 0.86 | PRKAG1 (0.37) | HAO1PRKAG1PRKAA1PRKAB1WNT3A | |
| SCHEMBL21296970 | 0.83 | ALPL (0.42) | HAO1PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL23319995 | 0.83 | HAO1 (0.46) | HAO1CCNCCDK8PRKAG1PRKAA1 | |
| SCHEMBL23320006 | 0.83 | HAO1 (0.46) | HAO1CCNCCDK8PRKAG1PRKAA1 | |
| SCHEMBL23319935 | 0.83 | HAO1 (0.48) | HAO1PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL23001685 | 0.83 | HAO1 (0.70) | HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143491-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | PHOENIX TISSUE REPAIR, INC. | 2023-05-11 | — | — | US | disclosed |
| US-20230143491-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | PHOENIX TISSUE REPAIR, INC. | 2023-05-11 | — | — | US | disclosed |
| US-20210403439-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | VENTHERA, INC. | 2021-12-30 | — | — | US | disclosed |
| CN-112399873-A | Triazole glycolate oxidase inhibitor | 奥凡生物科技公司 | 2021-02-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143491-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | XDH, DUOX1, PNPO | DYRK1A 1344/4885HAO1 6/4885PORCN 2040/4885 |
| US-20210403439-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | XDH, DUOX1, PNPO | DYRK1A 1344/4885HAO1 6/4885PORCN 2040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.