SCHEMBL24155178

SCHEMBL24155178

CCOC(=O)N1CC2C=CC1C(c1ccc(Cl)nc1)C2

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
DGAT1 O75907 1/20 0.38
PDE1C Q14123 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38
POLB P06746 1/20 0.35
PKM P14618 1/20 0.35
TERT O14746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382481 0.82 TSHR (0.46) KDM4EALDH1A1HTTPOLBPKM
SCHEMBL24155179 0.76 CHRNB2 (0.45) KMT2AALDH1A1CHRNB2CHRNA4
SCHEMBL24154668 0.76 CHRNB2 (0.49) KMT2AALDH1A1HPGDCHRNB2CHRNA4
SCHEMBL30116723 0.76 CHRNB2 (0.49) KMT2AALDH1A1HPGDCHRNB2CHRNA4
SCHEMBL15799144 0.72 KMT2A (0.50) RAB9AKMT2ADGAT1CHRNB2CHRNA4
SCHEMBL18518791 0.72 KMT2A (0.50) RAB9AKMT2ADGAT1CHRNB2CHRNA4
SCHEMBL25004995 0.72 KMT2A (0.50) RAB9AKMT2ADGAT1CHRNB2CHRNA4
SCHEMBL17259086 0.72 KMT2A (0.50) RAB9AKMT2ADGAT1CHRNB2CHRNA4
SCHEMBL15799143 0.72 KMT2A (0.50) RAB9AKMT2ADGAT1CHRNB2CHRNA4
SCHEMBL15805091 0.72 KMT2A (0.50) RAB9AKMT2ADGAT1CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225323-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL PHILIP MORRIS PRODUCTS S.A. (CH) 2023-07-20 US disclosed
US-20230225323-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL PHILIP MORRIS PRODUCTS S.A. (CH) 2023-07-20 US disclosed
WO-2021260029-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL PHILIP MORRIS PRODUCTS S.A. (CH) 2021-12-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225323-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL TRHDE, CUTA, PIGS RAB9A 391/4885KMT2A 808/4885KDM4E 1828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.