Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | ECE1 | P42892 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16415834 | 0.87 | MME (0.49) | MMEECE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8697150 | 0.84 | MME (0.47) | MMEECE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL43351 | 0.82 | MME (0.62) | MMEECE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL43350 | 0.82 | MME (0.62) | MMEECE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8932450 | 0.77 | MME (0.47) | MMEECE1MEN1KMT2AACE | |
| SCHEMBL73701 | 0.77 | L3MBTL1 (0.46) | MMEECE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL31510352 | 0.76 | ANPEP (0.48) | MMEECE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7411123 | 0.75 | MME (0.62) | MMEECE1MEN1KMT2AACE | |
| SCHEMBL7411127 | 0.75 | MME (0.62) | MMEECE1MEN1KMT2AACE | |
| SCHEMBL3103119 | 0.75 | FPR2 (0.54) | MMEECE1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106898-A1 | METHODS AND SYSTEMS FOR PREPARING IRREVERSIBLE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2011-09-09 | — | — | WO | disclosed |