Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 12/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19381471 | 1.00 | ALDH1A1 (0.37) | ALDH1A1TSHRPAOXKDM4AKDM4C | |
| SCHEMBL18373090 | 0.87 | ALDH1A1 (0.36) | ALDH1A1TSHRPAOXKDM4AKDM4C | |
| SCHEMBL19958158 | 0.86 | PAOX (0.32) | PAOX | |
| SCHEMBL20732425 | 0.85 | KDM4A (0.40) | ALDH1A1TSHRKDM4AKDM4CKDM5A | |
| SCHEMBL805213 | 0.85 | KDM4A (0.40) | ALDH1A1TSHRKDM4AKDM4CKDM5A | |
| SCHEMBL23253774 | 0.83 | — | — | |
| SCHEMBL26541398 | 0.81 | PAOX (0.40) | ALDH1A1PAOXKDM4CKDM5A | |
| SCHEMBL16560405 | 0.81 | S1PR2 (0.30) | — | |
| SCHEMBL19293312 | 0.80 | AOC3 (0.30) | — | |
| SCHEMBL14819876 | 0.78 | GPR84 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981780-A1 | ALPHA-V BETA-6 INTEGRIN LIGANDS AND USES THEREOF | Arrowhead Pharmaceuticals, Inc. (US) | 2022-04-13 | — | — | EP | disclosed |
| EP-3535397-B1 | ALPHA-V BETA-6 INTEGRIN LIGANDS AND USES THEREOF | ARROWHEAD PHARMACEUTICALS INC (US) | 2022-01-05 | — | — | EP | disclosed |