Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.42 |
| ▸ | TFPI | P10646 | 1/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.42 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNG | P07510 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRND | Q07001 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24158507 | 0.81 | ITGB3 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4TFPI | |
| SCHEMBL27272159 | 0.80 | CHRNA1 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4CALCRL | |
| SCHEMBL24158317 | 0.80 | NPC1 (0.46) | — | |
| SCHEMBL24158341 | 0.79 | TFPI (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4OPRL1 | |
| SCHEMBL24158387 | 0.79 | KEAP1 (0.50) | — | |
| SCHEMBL24183712 | 0.77 | NPC1 (0.61) | — | |
| SCHEMBL21389621 | 0.77 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL11067200 | 0.76 | ITGB3 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4CALCRL | |
| SCHEMBL11067208 | 0.76 | ITGB3 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4CALCRL | |
| SCHEMBL19234767 | 0.76 | GRIA1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3932935-A1 | ANTIBACTERIAL PEPTIDES | Centre National de la Recherche Scientifique (FR) | 2022-01-05 | — | — | EP | disclosed |