Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21983720 | 1.00 | MCHR1 (0.32) | MCHR1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL21983723 | 0.79 | CHRM2 (0.35) | MAPTRXFP1CYP1A2CYP2A6 | |
| SCHEMBL21983714 | 0.74 | CYP11B2 (0.43) | MCHR1ALDH1A1MAPTRXFP1CYP1A2 | |
| SCHEMBL21983915 | 0.71 | PRKACA (0.42) | KDM4EALDH1A1MAPTRXFP1CYP1A2 | |
| SCHEMBL21341398 | 0.71 | HSD11B1 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL21983715 | 0.70 | CYP2A6 (0.34) | KDM4EMAPTRXFP1CYP1A2CYP2A6 | |
| SCHEMBL21983718 | 0.68 | IDH1 (0.33) | MAPTRXFP1CYP1A2CYP2A6 | |
| SCHEMBL24630642 | 0.67 | — | — | |
| SCHEMBL24943916 | 0.67 | HSD11B1 (0.36) | — | |
| SCHEMBL24630640 | 0.66 | HSD11B1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3932404-A1 | METHOD FOR TREATING FATTY LIVER DISEASE AND/OR STEATOHEPATITIS | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2022-01-05 | — | — | EP | disclosed |