Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21983714 | 0.93 | CYP11B2 (0.43) | PRKACARPS6KB1GSK3BALDH1A1CYP1A2 | |
| SCHEMBL21983715 | 0.81 | CYP2A6 (0.34) | PRKACARPS6KB1GSK3BCYP1A2CYP11B2 | |
| SCHEMBL21983722 | 0.80 | HTR6 (0.34) | CYP11B2CYP11B1MAPTPRKDCRXFP1 | |
| SCHEMBL27739489 | 0.79 | TP53 (0.46) | PRKACARPS6KB1GSK3BALDH1A1CYP1A2 | |
| SCHEMBL28163312 | 0.79 | ALDH1A1 (0.42) | ALDH1A1CYP1A2MEN1CYP3A4CYP2D6 | |
| SCHEMBL21983718 | 0.79 | IDH1 (0.33) | CYP1A2CYP11B2CYP11B1MAPTCYP2A6 | |
| SCHEMBL21983723 | 0.78 | CHRM2 (0.35) | CYP1A2CYP11B2MAPTCYP2A6RXFP1 | |
| SCHEMBL16103839 | 0.77 | OPRM1 (0.44) | ALDH1A1CYP1A2MEN1CYP3A4CYP2D6 | |
| SCHEMBL28312616 | 0.74 | L3MBTL1 (0.61) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL28018819 | 0.71 | ALDH1A1 (0.52) | RPS6KB1ALDH1A1MEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3647311-B1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO LTD (CN) | 2023-11-01 | — | — | EP | disclosed |
| EP-3932404-A1 | METHOD FOR TREATING FATTY LIVER DISEASE AND/OR STEATOHEPATITIS | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2022-01-05 | — | — | EP | disclosed |
| EP-3647311-A1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2020-05-06 | — | — | EP | disclosed |