Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24943916 | 0.84 | HSD11B1 (0.36) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL24630640 | 0.83 | HSD11B1 (0.44) | HSD11B1 | |
| SCHEMBL21983714 | 0.80 | CYP11B2 (0.43) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL24159543 | 0.79 | MCHR1 (0.32) | MAPTRXFP1CYP1A2CYP2A6 | |
| SCHEMBL21983720 | 0.79 | MCHR1 (0.32) | MAPTRXFP1CYP1A2CYP2A6 | |
| SCHEMBL21983915 | 0.78 | PRKACA (0.42) | MAPTRXFP1CYP1A2CYP2A6CYP11B2 | |
| SCHEMBL21983715 | 0.76 | CYP2A6 (0.34) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL21983718 | 0.74 | IDH1 (0.33) | MAPTRXFP1CYP1A2CYP2A6CYP11B2 | |
| SCHEMBL20116278 | 0.74 | CHRM2 (0.43) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL21983722 | 0.72 | HTR6 (0.34) | CHRM2CHRM1CHRM3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3647311-B1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO LTD (CN) | 2023-11-01 | — | — | EP | disclosed |
| EP-3932404-A1 | METHOD FOR TREATING FATTY LIVER DISEASE AND/OR STEATOHEPATITIS | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2022-01-05 | — | — | EP | disclosed |
| EP-3647311-A1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2020-05-06 | — | — | EP | disclosed |