Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24160769 | 0.81 | — | — | |
| SCHEMBL24160612 | 0.81 | ALDH1A1 (0.32) | ALDH1A1TP53POLBKDM4EALOX15 | |
| SCHEMBL24160755 | 0.81 | KDM4E (0.38) | ALDH1A1TP53POLBDRD3KDM4E | |
| SCHEMBL23298737 | 0.81 | KDM4E (0.35) | ALDH1A1MEN1KMT2AMAPTTP53 | |
| SCHEMBL24160437 | 0.80 | NPSR1 (0.39) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL24159972 | 0.79 | TP53 (0.30) | ALDH1A1TP53POLB | |
| SCHEMBL23298823 | 0.78 | KDM4E (0.36) | ALDH1A1MEN1KMT2AMAPTTP53 | |
| SCHEMBL26289667 | 0.74 | KMT2A (0.37) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL23934357 | 0.74 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AMAPTTP53 | |
| SCHEMBL23129062 | 0.74 | MAPT (0.40) | ALDH1A1MEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3932922-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | ShanghaiTech University (CN) | 2022-01-05 | — | — | EP | disclosed |