Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SDCBP | O00560 | 3/20 | 0.34 |
| ▸ | SDC2 | P34741 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23298737 | 0.85 | KDM4E (0.35) | KDM4EALOX15ALDH1A1MAPTMEN1 | |
| SCHEMBL23129062 | 0.83 | MAPT (0.40) | KDM4EALOX15ALDH1A1MAPTMEN1 | |
| SCHEMBL23934357 | 0.83 | ALDH1A1 (0.37) | KDM4EALOX15ALDH1A1MAPTMEN1 | |
| SCHEMBL24160213 | 0.83 | THRB (0.38) | KDM4EALOX15ALDH1A1MAPTMEN1 | |
| SCHEMBL13258696 | 0.83 | THRB (0.38) | KDM4EALOX15ALDH1A1MAPTMEN1 | |
| SCHEMBL23739877 | 0.83 | MAPT (0.38) | KDM4EALOX15ALDH1A1MAPTMEN1 | |
| SCHEMBL26289667 | 0.82 | KMT2A (0.37) | KDM4EALOX15ALDH1A1MAPTMEN1 | |
| SCHEMBL24160755 | 0.81 | KDM4E (0.38) | KDM4EALOX15ALDH1A1POLBTP53 | |
| SCHEMBL23739470 | 0.80 | LMNA (0.36) | KDM4EALOX15ALDH1A1MAPTMEN1 | |
| SCHEMBL26443198 | 0.80 | ALDH1A1 (0.36) | KDM4EALOX15ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078301-A1 | PROTEIN DEGRADING AGENT AND USE THEREOF IN TREATMENT OF DISEASES | 上海科技大学 | 2021-04-29 | — | — | WO | disclosed |