Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23298823 | 0.85 | KDM4E (0.36) | KDM4EALOX15ALDH1A1POLBTP53 | |
| SCHEMBL24160755 | 0.83 | KDM4E (0.38) | KDM4EALOX15ALDH1A1POLBTP53 | |
| SCHEMBL24160437 | 0.82 | NPSR1 (0.39) | KDM4EALDH1A1POLBMAPTLMNA | |
| SCHEMBL24160612 | 0.82 | ALDH1A1 (0.32) | KDM4EALOX15ALDH1A1POLBTP53 | |
| SCHEMBL24160064 | 0.81 | ALDH1A1 (0.32) | KDM4EALOX15ALDH1A1POLBTP53 | |
| SCHEMBL24160213 | 0.79 | THRB (0.38) | KDM4EALOX15ALDH1A1POLBTP53 | |
| SCHEMBL23129062 | 0.79 | MAPT (0.40) | KDM4EALOX15ALDH1A1POLBMAPT | |
| SCHEMBL23934357 | 0.79 | ALDH1A1 (0.37) | KDM4EALOX15ALDH1A1POLBTP53 | |
| SCHEMBL23739877 | 0.78 | MAPT (0.38) | KDM4EALOX15ALDH1A1POLBTP53 | |
| SCHEMBL13258696 | 0.78 | THRB (0.38) | KDM4EALOX15ALDH1A1POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078301-A1 | PROTEIN DEGRADING AGENT AND USE THEREOF IN TREATMENT OF DISEASES | 上海科技大学 | 2021-04-29 | — | — | WO | disclosed |