Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968287 | 0.90 | KDM4E (0.56) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL25967980 | 0.83 | KDM4E (0.48) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL25968109 | 0.80 | ALDH1A1 (0.46) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL10334149 | 0.77 | KDM4E (0.75) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL24163320 | 0.73 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL25834338 | 0.72 | KDM4E (0.69) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9832407 | 0.72 | KDM4E (0.81) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL24162998 | 0.72 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL8310001 | 0.71 | KDM4E (0.67) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL16884170 | 0.71 | POLB (0.82) | KDM4EMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022006518-A1 | COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION | THE CLEVELAND CLINIC FOUNDATION (US) | 2022-01-06 | — | — | WO | disclosed |