Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968287 | 0.89 | KDM4E (0.56) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL25967980 | 0.87 | KDM4E (0.48) | ALDH1A1SMN1; SMN2GAAKDM4EMEN1 | |
| SCHEMBL24162997 | 0.80 | KDM4E (0.51) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL1143256 | 0.72 | SIGMAR1 (0.60) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL25969216 | 0.70 | HSD11B1 (0.56) | ALDH1A1SMN1; SMN2GAAKDM4EMEN1 | |
| SCHEMBL16883432 | 0.69 | GAA (0.64) | ALDH1A1SMN1; SMN2GAAKDM4EMEN1 | |
| SCHEMBL16883429 | 0.68 | GAA (0.67) | ALDH1A1SMN1; SMN2GAAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL10334149 | 0.68 | KDM4E (0.75) | ALDH1A1SMN1; SMN2GAAKDM4EMEN1 | |
| SCHEMBL13698452 | 0.67 | DRD2 (0.59) | ALDH1A1SMN1; SMN2GAACYP2C19 | |
| SCHEMBL14870361 | 0.66 | CYP1A2 (0.48) | ALDH1A1SMN1; SMN2GAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257350-A1 | COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION | THE CLEVELAND CLINIC FOUNDATION | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257350-A1 | COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION | CHAT, DCX, GAP43 | ALDH1A1 611/4885SMN1; SMN2 12/4885GAA 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.