Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25905782 | 0.85 | RXFP1 (0.45) | ALDH1A1HPGDRXFP1HTTTDP1 | |
| SCHEMBL194039 | 0.79 | RXFP1 (0.53) | SMN1; SMN2ALDH1A1HPGDRXFP1HTT | |
| SCHEMBL1004649 | 0.78 | ALDH1A1 (0.73) | SMN1; SMN2ALDH1A1HPGDHTTTDP1 | |
| SCHEMBL19459308 | 0.78 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1HPGDRXFP1HTT | |
| SCHEMBL5013530 | 0.78 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1HPGDRXFP1HTT | |
| SCHEMBL10055051 | 0.78 | RXFP1 (0.56) | SMN1; SMN2ALDH1A1HPGDRXFP1HTT | |
| SCHEMBL1663456 | 0.78 | HCAR3 (0.55) | SMN1; SMN2ALDH1A1HPGDRXFP1TDP1 | |
| SCHEMBL6842263 | 0.77 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1HPGDRXFP1HTT | |
| SCHEMBL1782141 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1HPGDRXFP1HTT | |
| SCHEMBL10024338 | 0.76 | RXFP1 (0.50) | SMN1; SMN2ALDH1A1HPGDRXFP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022006439-A2 | COMPOUND EMBODIMENTS FOR TREATING RETINAL DEGENERATION AND METHOD EMBODIMENTS OF MAKING AND USING THE SAME | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2022-01-06 | — | — | WO | disclosed |