Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.47 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.47 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.47 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | PRKCA | P17252 | 2/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412578 | 0.87 | POLM (0.46) | ALOX15ELANEPOLMPOLKPOLL | |
| SCHEMBL2416682 | 0.85 | PPARA (0.41) | FAAHPPARA | |
| SCHEMBL2416924 | 0.81 | MAPT (0.45) | ALOX15FAAHALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL5699358 | 0.81 | MAPT (0.45) | ALOX15FAAHALDH1A1CYP3A4HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL15285855 | 0.79 | ALOX15 (0.54) | ALOX15ELANEPOLMPOLKPOLL | |
| SCHEMBL2417275 | 0.79 | PSMB11 (0.48) | ALOX15FAAHALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL2417274 | 0.79 | PSMB11 (0.48) | ALOX15FAAHALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL2416106 | 0.77 | SMPD1 (0.43) | ALDH1A1TDP1HPGD | |
| SCHEMBL2412575 | 0.77 | LMNA (0.52) | TSHRTDP1MAPT | |
| SCHEMBL30666136 | 0.76 | POLM (0.67) | ALOX15ELANEPOLMPOLKPOLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109525-A1 | Aging-Related Circulating Particle-Associated Lipoprotein B Oxidase (apoBNOX) and Inhibitors Thereof | NOX TECHNOLOGIES, INC. (US) | 2011-09-09 | — | — | WO | disclosed |
| EP-1494658-B1 | NATURAL PHENOLIC PRODUCTS AND DERIVATIVES THEREOF FOR PROTECTION AGAINST NEURODEGENERATIVE DISEASES | PULEVA BIOTECH SA (ES) | 2006-01-04 | — | — | EP | disclosed |
| EP-1494658-A1 | NATURAL PHENOLIC PRODUCTS AND DERIVATIVES THEREOF FOR PROTECTION AGAINST NEURODEGENERATIVE DISEASES | PULEVA BIOTECH, S.A. (ES) | 2005-01-12 | — | — | EP | disclosed |
| US-20030236202-A1 | Natural products and derivatives thereof for protection against neurodegenerative diseases | PULEVA BIOTECH, S.A. (ES) | 2003-12-25 | — | — | US | disclosed |
| WO-2003082259-A1 | NATURAL PHENOLIC PRODUCTS AND DERIVATIVES THEREOF FOR PROTECTION AGAINST NEURODEGENERATIVE DISEASES | PULEVA BIOTECH, S.A. (ES) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236202-A1 | Natural products and derivatives thereof for protection against neurodegenerative diseases | SNCA, HTT, PARK7 | ALOX15 121/4885ELANE 1893/4885POLM 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.