Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.61 |
| ▸ | DHODH | Q02127 | 1/20 | 0.60 |
| ▸ | CSF1R | P07333 | 1/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24170257 | 0.87 | KCNMA1 (0.57) | KCNMA1DHODHCSF1RGRM4ALDH1A1 | |
| SCHEMBL92226 | 0.84 | RAB9A (0.57) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL12225787 | 0.83 | KCNMA1 (0.72) | KCNMA1DHODHGRM4ALDH1A1RAB9A | |
| SCHEMBL13164048 | 0.82 | HPGD (0.74) | KCNMA1DHODHCSF1RGRM4ALDH1A1 | |
| SCHEMBL7331410 | 0.80 | GRM4 (0.59) | KCNMA1DHODHGRM4ALDH1A1CYP2C9 | |
| SCHEMBL7332090 | 0.80 | PYGL (0.62) | KCNMA1DHODHGRM4ALDH1A1RAB9A | |
| SCHEMBL92574 | 0.78 | NPC1 (0.61) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11320747 | 0.78 | ALDH1A1 (0.64) | KCNMA1DHODHGRM4ALDH1A1CYP2C9 | |
| SCHEMBL91757 | 0.78 | HDAC3 (0.52) | ALDH1A1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL91556 | 0.78 | MAOB (0.57) | RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022000443-A1 | METHODS AND COMPOSITIONS FOR TARGETING TREGS USING CCR8 INHIBITORS | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2022-01-06 | — | — | WO | disclosed |