Sugi Predict

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SCHEMBL24176648

SCHEMBL24176648

CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(-c2cccc(N)c2)n1C(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FYN P06241 4/20 0.39
▸ NR1H2 P55055 6/20 0.38
▸ DYRK3 O43781 2/20 0.37
▸ CCNT1 O60563 2/20 0.37
▸ CCNA2 P20248 2/20 0.37
▸ CDK2 P24941 2/20 0.37
▸ CDK9 P50750 2/20 0.37
▸ CDK5 Q00535 2/20 0.37
▸ DYRK1A Q13627 2/20 0.37
▸ CDK5R1 Q15078 2/20 0.37
▸ DYRK2 Q92630 2/20 0.37
▸ DYRK1B Q9Y463 2/20 0.37
▸ BTK Q06187 1/20 0.35
▸ TTK P33981 3/20 0.33
▸ FGFR3 P22607 2/20 0.33
▸ KDR P35968 2/20 0.33
▸ NR1H3 Q13133 1/20 0.33
▸ HSP90AA1 P07900 1/20 0.33
▸ HSP90AB1 P08238 1/20 0.33
▸ CKS1B P61024 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24176651 0.86 NR1H2 (0.38) FYNNR1H2CDK2TTKNR1H3
SCHEMBL4066085 0.84 FYN (0.43) FYNNR1H2DYRK3CCNT1CCNA2
SCHEMBL24176646 0.83 HDAC2 (0.35) NR1H2TTKNR1H3
SCHEMBL24176881 0.83 SMN1; SMN2 (0.38) NR1H2NR1H3HSP90AA1HSP90AB1
SCHEMBL24176882 0.82 CFTR (0.38) FYNNR1H2TTKKDR
SCHEMBL24368122 0.80 MAP4K4 (0.41) FYNNR1H2DYRK3CCNT1CCNA2
SCHEMBL24176703 0.78 NR1H2 (0.38) NR1H2NR1H3CKS1BSKP1SKP2
SCHEMBL24368164 0.77 FYN (0.40) FYNNR1H2DYRK3CCNT1CCNA2
SCHEMBL13655217 0.74 NR1H2 (0.35) NR1H2TTKNR1H3
SCHEMBL10117875 0.73 NPC1 (0.35) NR1H2TTKNR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11582970-B2 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth NORTH CAROLINA STATE UNIVERSITY (US) 2023-02-21 — — US disclosed
US-20220000118-A1 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11582970-B2 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth DDC, IL4I1, ING2 FYN 4699/4885NR1H2 4595/4885DYRK3 2971/4885
US-20220000118-A1 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH DDC, IL4I1, ING2 FYN 4699/4885NR1H2 4595/4885DYRK3 2971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.