Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24176882 | 0.87 | CFTR (0.38) | NR1H2BACE1TTK | |
| SCHEMBL24176651 | 0.85 | NR1H2 (0.38) | NR1H2NR1H3GPR119TTKAAK1 | |
| SCHEMBL24176648 | 0.83 | FYN (0.39) | NR1H2NR1H3TTK | |
| SCHEMBL13655241 | 0.77 | SMN1; SMN2 (0.36) | NR1H2NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL13655217 | 0.75 | NR1H2 (0.35) | NR1H2NR1H3GPR119TTKAAK1 | |
| SCHEMBL10117875 | 0.74 | NPC1 (0.35) | NR1H2NR1H3GPR119TTKAAK1 | |
| SCHEMBL13663132 | 0.73 | PTPN1 (0.53) | NPC1RAB9A | |
| SCHEMBL30277630 | 0.73 | CYP1A1 (0.35) | HDAC1BACE1BACE2AAK1GABRG2 | |
| SCHEMBL10117698 | 0.72 | IDO1 (0.41) | NR1H2NR1H3GPR119AAK1NPC1 | |
| SCHEMBL13655220 | 0.71 | HDAC8 (0.43) | HDAC2HDAC1NR1H2AAK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11582970-B2 | 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220000118-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11582970-B2 | 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth | DDC, IL4I1, ING2 | HDAC2 213/4885HDAC1 685/4885NR1H2 4595/4885 |
| US-20220000118-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | DDC, IL4I1, ING2 | HDAC2 213/4885HDAC1 685/4885NR1H2 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.