Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 4/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5413155 | 0.80 | L3MBTL1 (0.55) | SLC6A2SLC6A4CACNA1GCACNA1HCACNA1I | |
| SCHEMBL14486495 | 0.80 | SLC6A2 (0.45) | SLC6A2SLC6A4CACNA1GCACNA1HCACNA1I | |
| SCHEMBL22957693 | 0.79 | ATM (0.46) | SLC6A2SLC6A4CACNA1GCACNA1HCACNA1I | |
| SCHEMBL2662469 | 0.79 | SLC6A2 (0.49) | SLC6A2SLC6A4GABRA1GABRB2 | |
| SCHEMBL12394754 | 0.78 | GABRA1 (0.45) | SLC6A2SLC6A4GABRA1GABRB2CACNA1G | |
| SCHEMBL12461613 | 0.78 | L3MBTL1 (0.56) | SLC6A2SLC6A4GABRA1GABRB2MEN1 | |
| SCHEMBL12960409 | 0.77 | KCNH2 (0.44) | GABRA1GABRB2CTSSCTSKKDM4E | |
| SCHEMBL22389474 | 0.77 | RIPK1 (0.57) | SLC6A2SLC6A4CACNA1GCACNA1HCACNA1I | |
| SCHEMBL24180069 | 0.77 | AR (0.47) | SLC6A2SLC6A4CACNA1GCACNA1HCACNA1I | |
| SCHEMBL28288419 | 0.77 | MAPT (0.52) | SLC6A2SLC6A4KDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704118-B1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-01-12 | — | — | EP | disclosed |