Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ABHD10 | Q9NUJ1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180152 | 0.94 | CYP3A4 (0.33) | CYP3A4ALDH1A1TSHRCYP2C19HPGD | |
| SCHEMBL24180238 | 0.93 | EIF4A1 (0.38) | CYP3A4ALDH1A1TSHRCYP2C19HPGD | |
| SCHEMBL24180234 | 0.88 | MEN1 (0.33) | CYP3A4ALDH1A1TSHRCYP2C19HPGD | |
| SCHEMBL24180189 | 0.87 | EIF4A1 (0.39) | CYP3A4ALDH1A1TSHRCYP2C19HPGD | |
| SCHEMBL24426898 | 0.87 | EIF4A1 (0.35) | CYP3A4ALDH1A1TSHRCYP2C19KDM4E | |
| SCHEMBL24426987 | 0.86 | PNLIP (0.38) | CYP3A4ALDH1A1TSHRCYP2C19HPGD | |
| SCHEMBL24180190 | 0.85 | EIF4A1 (0.38) | CYP3A4ALDH1A1TSHRCYP2C19HPGD | |
| SCHEMBL24426990 | 0.82 | EIF4A1 (0.38) | CYP3A4ALDH1A1TSHRCYP2C19HPGD | |
| SCHEMBL24180202 | 0.81 | ALDH1A1 (0.34) | ALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL24426991 | 0.81 | CYP19A1 (0.34) | CYP3A4ALDH1A1TSHRCYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3418273-B1 | FLAVAGLINE DERIVATIVES | PF MEDICAMENT (FR) | 2022-01-12 | — | — | EP | disclosed |