Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A1 | P60842 | 12/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180189 | 0.95 | EIF4A1 (0.39) | EIF4A1CYP3A4ALDH1A1HIF1ATSHR | |
| SCHEMBL24426898 | 0.94 | EIF4A1 (0.35) | EIF4A1CYP3A4ALDH1A1HIF1ATSHR | |
| SCHEMBL24180246 | 0.93 | PPARG (0.34) | EIF4A1CYP3A4ALDH1A1HIF1ATSHR | |
| SCHEMBL24180152 | 0.92 | CYP3A4 (0.33) | EIF4A1CYP3A4ALDH1A1HIF1ATSHR | |
| SCHEMBL24180190 | 0.92 | EIF4A1 (0.38) | EIF4A1CYP3A4ALDH1A1HIF1ATSHR | |
| SCHEMBL24426990 | 0.90 | EIF4A1 (0.38) | EIF4A1CYP3A4ALDH1A1HIF1ATSHR | |
| SCHEMBL24180234 | 0.86 | MEN1 (0.33) | CYP3A4ALDH1A1TSHRCYP2C19MAPK1 | |
| SCHEMBL24426987 | 0.85 | PNLIP (0.38) | EIF4A1CYP3A4ALDH1A1HIF1ATSHR | |
| SCHEMBL24426912 | 0.83 | AGTR1 (0.37) | EIF4A1CYP3A4ALDH1A1HIF1ATSHR | |
| SCHEMBL24180202 | 0.81 | ALDH1A1 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998257-A1 | FLAVAGLINE DERIVATIVES | PIERRE FABRE MEDICAMENT (FR) | 2022-05-18 | — | — | EP | disclosed |
| EP-3418273-B1 | FLAVAGLINE DERIVATIVES | PF MEDICAMENT (FR) | 2022-01-12 | — | — | EP | disclosed |