Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD10 | Q9NUJ1 | 1/20 | 0.37 |
| ▸ | EIF4A1 | P60842 | 6/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180127 | 0.92 | ABHD10 (0.38) | ABHD10EIF4A1NFKB1RELACYP3A4 | |
| SCHEMBL24180133 | 0.88 | ABHD10 (0.47) | ABHD10EIF4A1NFKB1RELACYP3A4 | |
| SCHEMBL24180150 | 0.83 | ABHD10 (0.39) | ABHD10EIF4A1NFKB1RELACYP3A4 | |
| SCHEMBL17396559 | 0.77 | ABHD10 (0.61) | ABHD10EIF4A1NFKB1RELACYP3A4 | |
| SCHEMBL17396562 | 0.77 | ABHD10 (0.61) | ABHD10EIF4A1NFKB1RELACYP3A4 | |
| SCHEMBL24426931 | 0.76 | ALDH1A1 (0.34) | CYP3A4ALDH1A1TSHRCYP2C19KDM4E | |
| SCHEMBL24180194 | 0.76 | ABHD10 (0.39) | ABHD10EIF4A1NFKB1RELACYP3A4 | |
| SCHEMBL18862721 | 0.75 | ABHD10 (0.50) | ABHD10EIF4A1NFKB1RELACYP3A4 | |
| SCHEMBL24426915 | 0.73 | EIF4A1 (0.45) | ABHD10EIF4A1CYP3A4ALDH1A1HIF1A | |
| SCHEMBL17396618 | 0.72 | ABHD10 (0.63) | ABHD10EIF4A1NFKB1RELACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3418273-B1 | FLAVAGLINE DERIVATIVES | PF MEDICAMENT (FR) | 2022-01-12 | — | — | EP | disclosed |