Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 3/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | PNLIP | P16233 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180258 | 0.95 | ALDH1A1 (0.35) | ALDH1A1CYP3A4HPGDKDM4EMAPK1 | |
| SCHEMBL24426905 | 0.91 | PNLIP (0.40) | ALDH1A1CYP3A4HPGDKDM4EMAPK1 | |
| SCHEMBL24180234 | 0.80 | MEN1 (0.33) | ALDH1A1CYP3A4HPGDKDM4EMAPK1 | |
| SCHEMBL24180246 | 0.79 | PPARG (0.34) | ALDH1A1CYP3A4HPGDKDM4EMAPK1 | |
| SCHEMBL24180152 | 0.79 | CYP3A4 (0.33) | ALDH1A1CYP3A4HPGDKDM4EMAPK1 | |
| SCHEMBL24180238 | 0.78 | EIF4A1 (0.38) | ALDH1A1CYP3A4HPGDMAPK1TSHR | |
| SCHEMBL20006331 | 0.77 | CYP3A4 (0.41) | ALDH1A1CYP3A4TSHRCYP2C19MEN1 | |
| SCHEMBL24180259 | 0.77 | ALDH1A1 (0.32) | ALDH1A1CYP3A4HPGDKDM4EMAPK1 | |
| SCHEMBL24180251 | 0.76 | ABHD10 (0.37) | ALDH1A1CYP3A4HPGDKDM4EMAPK1 | |
| SCHEMBL24180151 | 0.75 | KDM4E (0.39) | ALDH1A1CYP3A4HPGDKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998257-A1 | FLAVAGLINE DERIVATIVES | PIERRE FABRE MEDICAMENT (FR) | 2022-05-18 | — | — | EP | disclosed |