Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 12/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141699 | 0.81 | MTNR1A (0.59) | KDM4ETSHRALDH1A1MAPTHTT | |
| SCHEMBL16150685 | 0.80 | MAPT (0.47) | KDM4EHSD17B10ALDH1A1MAPTNPSR1 | |
| SCHEMBL7960876 | 0.79 | F10 (0.50) | KDM4ETSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL24187363 | 0.79 | TSHR (0.71) | KDM4ETSHRPOLBHSD17B10ALDH1A1 | |
| SCHEMBL24187458 | 0.78 | MTNR1A (0.46) | KDM4EMAPTTDP1NPSR1SMN1; SMN2 | |
| SCHEMBL15563812 | 0.78 | DRD2 (0.44) | KDM4ETSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL17554396 | 0.78 | TSHR (0.78) | KDM4ETSHRPOLBHSD17B10ALDH1A1 | |
| SCHEMBL16151412 | 0.78 | GAA (0.43) | KDM4EPOLBALDH1A1MAPTTDP1 | |
| SCHEMBL27141102 | 0.77 | DRD2 (0.39) | KDM4ETSHRALDH1A1MAPTTDP1 | |
| SCHEMBL29153650 | 0.77 | MTNR1A (0.42) | KDM4EALDH1A1MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022007866-A1 | FUSED TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 深圳信立泰药业股份有限公司 | 2022-01-13 | — | — | WO | disclosed |