Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 2/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19302498 | 0.85 | SIGMAR1 (0.39) | PDK2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL21036238 | 0.77 | PDK2 (0.37) | PDK2SIGMAR1CACNA1H | |
| SCHEMBL21035484 | 0.77 | CACNA1H (0.36) | OPRL1SIGMAR1CA2CACNA1H | |
| SCHEMBL24196140 | 0.77 | LOXL2 (0.41) | SIGMAR1CACNA1HMAOB | |
| SCHEMBL26014791 | 0.76 | PTGS1 (0.40) | SIGMAR1 | |
| SCHEMBL25735734 | 0.76 | PDK2 (0.40) | PDK2SIGMAR1CACNA1H | |
| SCHEMBL9560929 | 0.75 | LPL (0.38) | PDK2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL18969775 | 0.74 | KIF11 (0.40) | PDK2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL25801644 | 0.73 | CACNA1H (0.39) | SIGMAR1CACNA1H | |
| SCHEMBL15981142 | 0.71 | ESR1 (0.41) | PDK2OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022010880-A1 | KCNT1 INHIBITORS AND METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2022-01-13 | — | — | WO | disclosed |